What Is Half-Life in the Context of Medication for Pregnant Women?
Question by rcazac: What is half-life in the context of medication for pregnant women?
I have the following sentence
“Women of child-bearing potential, defined as all women physiologically capable of becoming pregnant, must use effective contraception during the study and for 5 days (5 half-lives) after treatment”
What is “half life” in this context? Is there a synonym for it?
Best answer:
Answer by Big Daddy
If you put a quantity of a substance in the body at one time, it is not all removed at one time. The half-life refers to the time that passes before half of the substance has been removed (metabolized, excreted, deactivated, etc.) It is not related (other than the name) to radioactivity or other exponential processes that use the same term.
Importantly, you cannot model the quantity at a given time by using the exponential curves appropriate for radioactive decay.
From context, it appears the half-life of this medication is approximately one day.
Know better? Leave your own answer in the comments!
Fire forces evacuation of drug treatment facility
There were no injuries in the 8:45 p.m. fire at DACCO, a substance abuse treatment facility located at 4422 E. Columbus Dr., authorities said. The fire was caused by an electrical short in an overhead door motor. More than 30 firefighters contained the …
Read more on Tbo.com
Substance-abuse treatment program goals bring Republican Chris Christie …
The New Jersey Republican governor appeared on Wednesday with former Garden State governor Jim McGreevey, a Democrat, at a local jail to meet with a group of incarcerated women participating in a substance-abuse-treatment program. RELATED: JIM …
Read more on New York Daily News
More Substance Treatment Information…