Archive for the ‘Methadone Detox’ Category
Methadone Detox: QTc Interval Screening for Cardiac Risk in Methadone Treatment of Opioid Dependence.
QTc interval screening for cardiac risk in methadone treatment of opioid dependence.
Cochrane Database Syst Rev. 2013 Jun 20; 6: CD008939
Pani PP, Trogu E, Maremmani I, Pacini M
Solving the Problem of Overprescribed Opioids – TheFix.com
Solving the Problem of Overprescribed Opioids – TheFix.com
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Solving the Problem of Overprescribed Opioids
TheFix.com Although nobody that I spoke with endorsed the idea of rapid detox fromopioids, many patients who are seeking treatment are admitted to inpatient detox, usually followed by a rehabilitation program. Others opt for Medication Assisted Therapy with a … |
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Methadone Detox: Quantitative Analysis of 26 Opioids, Cocaine, and Their Metabolites in Human Blood by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry.
Quantitative Analysis of 26 Opioids, Cocaine, and Their Metabolites in Human Blood by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry.
Ther Drug Monit. 2013 Jun 18;
Fernández MD, Wille SM, Kummer N, Di Fazio V, Ruyssinckx E, Samyn N
: A sensitive and selective ultra performance liquid chromatographic-tandem mass spectrometric method was developed and fully validated for the simultaneous determination of (in order of chromatographic elution) methylecgonine, pholcodine, morphine, hydromorphone, oxymorphone, norcodeine, codeine, dihydrocodeine, oxycodone, 6-Monoacetylmorphine (6-MAM), hydrocodone, ethylmorphine, norfentanyl, benzoylecgonine, tramadol, normeperidine, meperidine, cocaine, pentazocine, cocaethylene, fentanyl, norbuprenorphine, 2-ethylidine-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), buprenorphine, propoxyphene, and methadone in blood. The matrixes analyzed during the validation experiments were as follows: citrated blank plasma for calibrators, fluoride blank plasma for internal quality control (QC), lyophilized serum for external QC, fluoride plasma and whole blood for authentic samples, and lyophilized serum and whole blood for proficiency testing schemes. Samples were extracted with cation exchange solid-phase extraction cartridges. The target drugs were separated and quantified in a chromatographic run of 8.1 minutes using 0.1% formic acid in water and methanol (with 0.1% formic acid) as mobile phase. The limit of quantification ranged from 0.5 to 2.5 ng/mL depending on the compound and the therapeutic concentration. The intra- and interassay precision was less than 15% for all the compounds (except for pentazocine and EDDP, which was <20%) determined with 2 internal and 2 external QC samples, and the bias was within ±15% (except for methylecgonine, which was <20%). Extraction efficiency was greater than 70% for all the compounds except for EDDP. Matrix effects were evaluated with authentic blood samples (n = 10), and they ranged from 47 to 95%, but they were compensated for most analytes using deuterated analogs as internal standards. Prepared samples were stable for 62 hours in the autosampler. This method was successfully applied to authentic samples (n = 120), involving the use of heroin, cocaine, tramadol, and methadone, and to proficiency testing schemes. HubMed – Methadone
Methadone Detox: Louisville Company Receives $15 Million Federal Grant to Study Medication for … – the Courier-Journal
Louisville company receives million federal grant to study medication for … – The Courier-Journal
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Louisville company receives $ 15 million federal grant to study medication for …
The Courier-Journal Officials pointed out that only two federally-approved drugs are currently available to treat opioid withdrawal: methadone and buprenorphine. “Both are opiate products that effectively operate as replacement or substitution therapies, but both have … |
Taking the fight to the streets – The Coast Halifax (blog)
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Taking the fight to the streets
The Coast Halifax (blog) The next minute she could wind up trying to gently broach the subject of detox with a homeless man who's been kicked out of several shelters due to his substance abuse. Then she … They also help people get to and from their methadone appointments. |
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Business News and Markets: As It Happened, June 20, 2013 – Telegraph.co.uk
Business news and markets: as it happened, June 20, 2013 – Telegraph.co.uk
Telegraph.co.uk |
Business news and markets: as it happened, June 20, 2013
Telegraph.co.uk Quote The thought of QE / Methadone withdrawal appears to be hitting the markets, with shakes and shivers after the Bernanke press conference. The FOMC statement was anodyne, with slightly improved economic forecasts with regards to 2014 growth and … |
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Business News and Markets: Live – Telegraph.co.uk
Business news and markets: live – Telegraph.co.uk
Telegraph.co.uk |
Business news and markets: live
Telegraph.co.uk Quote The thought of QE / Methadone withdrawal appears to be hitting the markets, with shakes and shivers after the Bernanke press conference. The FOMC statement was anodyne, with slightly improved economic forecasts with regards to 2014 growth and … |
Methadone detox – Detox day 8.
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