Archive for the ‘Methadone Clinics’ Category

Open Question: Do they 11 panel drug test at the methadone clinic test for how much methadone etc is in your system?

Filed under: Methadone Clinics

Methadone clinic supported – London Free Press

Filed under: Methadone Clinics

Methadone clinic supported London Free Press STRATFORD – Stratford could get a methadone clinic and better services for addicts as they go through withdrawal. A methadone clinic and detox services were identified as urgent priorities by both service providers and service users in a recently …

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Mayor, experts: City needs methadone clinic – Berkshire Eagle

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iBerkshires.com

Mayor, experts: City needs methadone clinic Berkshire Eagle PITTSFIELD — In an attempt to allay concerns surrounding a controversial methadone clinic planned for the city, Mayor Daniel L. Bianchi on Monday told a forum of concerned citizens that — wherever it's finally located — the city will only benefit … Pittsfield residents voice methadone clinic concerns at public meetingYNN Hudson Valley Confidentiality Sparks Ire At Pittsfield Methadone MeetingiBerkshires.com all 4 news articles »

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Opposition to Spectrum clinic plans nothing new – Berkshire Eagle

Filed under: Methadone Clinics

Opposition to Spectrum clinic plans nothing new Berkshire Eagle PITTSFIELD — This isn't the first time Spectrum Health Systems, the company planning to open a methadone clinic in Pittsfield, has faced fierce, homegrown opposition. Around the state, Spectrum's plans to open treatment centers for heroin and …

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Doctors say methadone program ‘gridlocked’ – StarPhoenix

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Doctors say methadone program 'gridlocked' StarPhoenix Dr. Morris Markentin, who practices at the West Side Community Clinic and is one of four active Saskatoon doctors with an exemption to prescribe methadone, says he turned away 27 people last week looking start the program. Markentin said methadone is … and more »

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A day at a methadone clinic… – This video was uploaded from an Android phone.

Lufkin methadone clinic says ‘it’s business as usual’ – KTRE

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Lufkin methadone clinic says 'it's business as usual' KTRE It will be business as usual at The Methadone Clinic of East Texas, despite federal charges for two key employees. A federal grand jury indicted Daniel Kubisty and Edward Jacobs for planning to burn down their competition, The Add-Life Recovery Center … and more »

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Proposed move of methadone clinic near schools causes some concern – BurlingtonFreePress.com

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Proposed move of methadone clinic near schools causes some concern BurlingtonFreePress.com The operator of the state's largest methadone clinic wants to move the facility from Burlington to a medical office building at 364 Dorset St., about a quarter mile from South Burlington's middle and high schools. The proposed move is being watched …

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Pharmacological Characterization of the Mechanisms Involved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone.

Filed under: Methadone Clinics

Int J Cell Biol. 2012; 2012: 642482
Perez-Alvarez S, Solesio ME, Cuenca-Lopez MD, Melero-Fernández de Mera RM, Villalobos C, Kmita H, Galindo MF, Jordán J

Previously, we have shown that SH-SY5Y cells exposed to high concentrations of methadone died due to a necrotic-like cell death mechanism related to delayed calcium deregulation (DCD). In this study, we show that, in terms of their Ca(2+) responses to 0.5?mM methadone, SH-SY5Y cells can be pooled into four different groups. In a broad pharmacological survey, the relevance of different Ca(2+)-related mechanisms on methadone-induced DCD was investigated including extracellular calcium, L-type Ca(2+) channels, ?-opioid receptor, mitochondrial inner membrane potential, mitochondrial ATP synthesis, mitochondrial Ca(2+)/2Na(+)-exchanger, reactive oxygen species, and mitochondrial permeability transition. Only those compounds targeting mitochondria such as oligomycin, FCCP, CGP 37157, and cyclosporine A were able to amend methadone-induced Ca(2+) dyshomeostasis suggesting that methadone induces DCD by modulating the ability of mitochondria to handle Ca(2+). Consistently, mitochondria became dramatically shorter and rounder in the presence of methadone. Furthermore, analysis of oxygen uptake by isolated rat liver mitochondria suggested that methadone affected mitochondrial Ca(2+) uptake in a respiratory substrate-dependent way. We conclude that methadone causes failure of intracellular Ca(2+) homeostasis, and this effect is associated with morphological and functional changes of mitochondria. Likely, this mechanism contributes to degenerative side effects associated with methadone treatment.
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Mayor, experts: City needs methadone clinic – Berkshire Eagle

Filed under: Methadone Clinics

iBerkshires.com

Mayor, experts: City needs methadone clinic Berkshire Eagle PITTSFIELD — In an attempt to allay concerns surrounding a controversial methadone clinic planned for the city, Mayor Daniel L. Bianchi on Monday told a forum of concerned citizens that — wherever it's finally located — the city will only benefit … Pittsfield residents voice methadone clinic concerns at public meetingYNN Hudson Valley Confidentiality Sparks Ire At Pittsfield Methadone MeetingiBerkshires.com all 4 news articles »

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Peekskill Officials Fighting Methadone Clinic – The Daily Voice

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Peekskill Officials Fighting Methadone Clinic The Daily Voice Mayor Mary Foster told residents at the July 16 Common Council meeting that Common Council members were not aware of the Planning Board's approval of a methadone clinic at 3 Corporate Drive. The clinic is intended to replace one currently operating … Peekskill backpedalling on methadone clinic approvalThe Journal News | LoHud.com Methadone Clinic Back to the Planning BoardPatch.com all 4 news articles »